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Thesis

The role of protein arginine methylation in T-lymphocyte activation

Abstract:

T-lymphocytes are an essential cell type of the adaptive immune system. Due to their importance in immune responses and disorders, the molecular mechanisms leading to T-lymphocyte activation have been the subject of extensive research which has translated into important therapeutic developments. Early signalling events involving tyrosine phosphorylation are well characterised. However, later events involving other post-translational modifications are less well understood. Several studies h...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Oreste Acuto
Oxford college:
Keble College
Role:
Author
More by this author
Division:
MSD
Department:
Pathology Dunn School
Role:
Author

Contributors

Division:
MSD
Department:
Pathology Dunn School
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

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