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Journal article

PARP, transcription and chromatin modeling

Abstract:

Compaction mode of chromatin and chromatin highly organised structures regulate gene expression. Posttranslational modifications, histone variants and chromatin remodelers modulate the compaction, structure and therefore function of specific regions of chromatin. The generation of poly(ADP-ribose) (PAR) is emerging as one of the key signalling events on sites undergoing chromatin structure modulation. PAR is generated locally in response to stresses. These include genotoxic stress but also di...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.semcdb.2016.09.014

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Seminars in Cell and Developmental Biology Journal website
Volume:
63
Pages:
102-113
Publication date:
2016-09-24
Acceptance date:
2016-09-23
DOI:
EISSN:
1096-3634
ISSN:
1084-9521
Pmid:
27677453
Source identifiers:
648097
Language:
English
Keywords:
Pubs id:
pubs:648097
UUID:
uuid:212223e2-1cd0-4093-addf-c85df58996a3
Local pid:
pubs:648097
Deposit date:
2017-09-08

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