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Thesis

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches

Abstract:

There is an urgent need for improvements to existing vaccine delivery technologies to run parallel with the development of new-generation vaccines. The burdens of needle-based immunisation strategies are exacerbated by poor resource provision in such areas as sub-Saharan Africa, where annual malaria mortality stands at 860,000. Needle-free delivery of vaccine to the skin holds promise for improved immunogenicity with lower doses of vaccine, in addition to significant logistical advantages....

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
The Jenner Institute
Oxford college:
Mansfield College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:2155c639-bcc8-49e0-b415-a5d353aacba3
Local pid:
ora:9843
Deposit date:
2015-01-30

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