Journal article icon

Journal article

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

Abstract:

The trajectories of acquired immunity to severe acute respiratory syndrome coronavirus 2 infection are not fully understood. We present a detailed longitudinal cohort study of UK healthcare workers prior to vaccination, presenting April-June 2020 with asymptomatic or symptomatic infection. Here we show a highly variable range of responses, some of which (T cell interferon-gamma ELISpot, N-specific antibody) wane over time, while others (spike-specific antibody, B cell memory ELISpot) are stab...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/s41467-022-28898-1

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0001-9885-3535
More by this author
Role:
Author
ORCID:
0000-0002-2426-3097
More by this author
Role:
Author
ORCID:
0000-0001-7774-7215
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
ORCID:
0000-0002-6902-9886
Expand authors...

Contributors

Role:
Contributor
Role:
Contributor
DH | National Institute for Health Research (NIHR) More from this funder
Publisher:
Springer Nature Publisher's website
Journal:
Nature Communications Journal website
Volume:
13
Article number:
1251
Publication date:
2022-03-10
Acceptance date:
2022-02-17
DOI:
EISSN:
2041-1723
Pmid:
35273178
Language:
English
Keywords:
Pubs id:
1243557
Local pid:
pubs:1243557
Deposit date:
2022-03-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP