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Thesis

Immune regulatory networks in inflammation-driven cancer

Abstract:

The incidence of colorectal cancer (CRC) is increasing and the prognosis for patients with advanced or metastatic disease is relatively poor. Immunotherapies hold great promise, but deploying them effectively in CRC patients will require further knowledge of the complex cellular and molecular interactions that occur between intestinal tumours and the host immune system. The objective of this study is to understand the mechanisms by which lack of immune cell regulation in the gut can drive ...

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Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author

Contributors

Sub department:
Kennedy Institute for Rheumatology
Role:
Supervisor
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Funding agency for:
Franchini, F
Grant:
C38302/A13012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:2314081e-8c3f-43c7-9ea6-edf43430a43c
Deposit date:
2018-07-08

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