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Journal article

Magnesium deficiency prevents high-fat-diet-induced obesity in mice

Abstract:

Aims/hypothesis: Hypomagnesaemia (blood Mg2+ ≺0.7 mmol/l) is a common phenomenon in individuals with type 2 diabetes. However, it remains unknown how a low blood Mg2+ concentration affects lipid and energy metabolism. Therefore, the importance of Mg2+ in obesity and type 2 diabetes has been largely neglected to date. This study aims to determine the effects of hypomagnesaemia on energy homeostasis and lipid metabolism. Methods: Mice (n = 12/group) were fed either a low-fat diet (LFD) or a hig...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00125-018-4680-5

Authors


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Radboud Institute for Molecular Life Sciences More from this funder
Netherlands Organization for Scientific Research More from this funder
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Publisher:
Springer Publisher's website
Journal:
Diabetologia Journal website
Volume:
61
Issue:
9
Pages:
2030-2042
Publication date:
2018-07-09
Acceptance date:
2018-06-01
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
Pmid:
29987474
Source identifiers:
869564
Language:
English
Keywords:
Pubs id:
pubs:869564
UUID:
uuid:26033a94-d022-4482-9005-da297317c8ab
Local pid:
pubs:869564
Deposit date:
2018-08-30

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