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Large scale association analysis identifies three susceptibility loci for coronary artery disease.

Abstract:

Genome wide association studies (GWAS) and their replications that have associated DNA variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are predominantly based on populations of European or Eastern Asian descent. Replication of the most significantly associated polymorphisms in multiple populations with distinctive genetic backgrounds and lifestyles is crucial to the understanding of the pathophysiology of a multifactorial disease like CAD. We have used our Lebane...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pone.0029427

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
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Journal:
PloS one
Volume:
6
Issue:
12
Pages:
e29427
Publication date:
2011-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
222378
Language:
English
Keywords:
UUID:
uuid:27c8b891-444c-46e0-9568-8b76e0468309
Local pid:
pubs:222378
Deposit date:
2012-12-19

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