Thesis
The synthesis of branched sugars and iminosugars
- Abstract:
-
Iminosugars, carbohydrate analogues in which nitrogen replaces the endocyclic oxygen, have attracted much interest due to their biological activity. Iminosugars inhibit carbohydrate-processing enzymes, thereby affecting many biological processes. Several iminosugars are licensed drugs, with many more compounds undergoing clinical trials. The main subject of this thesis is the synthesis and evaluation of novel iminosugars, particularly the effects of structural modifications on the biologic...
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Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:2a511d58-f626-4f7e-aebc-f595b147827a
- Local pid:
- ora:11641
- Deposit date:
- 2015-06-11
Terms of use
- Copyright holder:
- Loren Parry
- Copyright date:
- 2011
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