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Journal article

Validation of diffusion tensor MRI measurements of cardiac microstructure with structure tensor synchrotron radiation imaging

Abstract:

BACKGROUND: Diffusion tensor imaging (DTI) is widely used to assess tissue microstructure non-invasively. Cardiac DTI enables inference of cell and sheetlet orientations, which are altered under pathological conditions. However, DTI is affected by many factors, therefore robust validation is critical. Existing histological validation is intrinsically flawed, since it requires further tissue processing leading to sample distortion, is routinely limited in field-of-view and requires reconstruct...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12968-017-0342-x

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Funding agency for:
Schneider, J
Grant:
Senior Basic Science Research Fellow (FS/11/50/29038
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Grant:
PG/13/33/30210
RG/13/8/30266
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Publisher:
BioMed Central Publisher's website
Journal:
Journal of Cardiovascular Magnetic Resonance Journal website
Volume:
19
Issue:
1
Article number:
31
Publication date:
2017-03-10
Acceptance date:
2017-02-16
DOI:
EISSN:
1532-429X
ISSN:
1097-6647
Source identifiers:
685337
Language:
English
Keywords:
Pubs id:
pubs:685337
UUID:
uuid:2c026754-c8c7-451f-89fd-04cd4e598031
Local pid:
pubs:685337
Deposit date:
2017-07-25

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