Journal article
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- Abstract:
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In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood pressure SNPs and 53 rare variants in genome-wide association studies of systolic, diastolic and pulse pressure in up to 776,078 participants from the Million Veteran Program (MVP) and collaborating studies, with analysis of the blood pressure clinical phenome in MVP. Ou...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 280.8KB)
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- Publisher copy:
- 10.1038/s41588-018-0303-9
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 51
- Pages:
- 51–62
- Publication date:
- 2018-12-21
- Acceptance date:
- 2018-10-31
- DOI:
- EISSN:
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1546-1718
- ISSN:
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1061-4036
- Pmid:
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30578418
- Source identifiers:
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954629
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:954629
- UUID:
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uuid:2c9268c2-5ab6-4f76-bf27-c2fc18804e24
- Local pid:
- pubs:954629
- Deposit date:
- 2019-01-18
Terms of use
- Copyright holder:
- Giri, et al
- Copyright date:
- 2018
- Notes:
- © Giri, et.al. 2018
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