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Investigating the effect of H3K4 and H3K79 methylation on gene expression noise in Saccharomyces cerevisiae

Abstract:

Gene expression noise, the stochastic variation in a gene’s protein level in a population of genetically identical cells, has been shown to play an important role in several biological processes. However, it is not yet understood how gene expression noise is controlled. Following Newman et al. (2006)’s work, where a library of GFP-tagged genes at COOH termini and FACS was used to analyse noise levels in S. cerevisiae for 2,204 genes, we discovered at the genome-wide level a st...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Role:
Supervisor
Saudi Arabian government More from this funder
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:2c93c7a1-a515-4175-96a7-ea09467715cd
Deposit date:
2019-02-09

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