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GAT: a simulation framework for testing the association of genomic intervals

Abstract:

Motivation: A common question in genomic analysis is whether two sets of genomic intervals overlap significantly. This question arises, for example, when interpreting ChIP-Seq or RNA-Seq data in functional terms. Because genome organization is complex, answering this question is non-trivial.

Summary: We present Genomic Association Test (GAT), a tool for estimating the significance of overlap between multiple sets of genomic intervals. GAT implements...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/bioinformatics/btt343

Authors


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Institution:
Medical Research Council
Department:
CGAT Programme and Functional Genomics Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
Medical Research Council
Department:
CGAT Programme and Functional Genomics Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author

Contributors

Role:
Editor
Medical Research Council More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Bioinformatics Journal website
Volume:
29
Issue:
16
Pages:
2046-2048
Publication date:
2013-08-01
DOI:
EISSN:
1460-2059
ISSN:
1367-4803
Language:
English
Keywords:
Subjects:
UUID:
uuid:2d59dfc1-13fe-45f4-ac5c-4d08a559654c
Local pid:
ora:7772
Deposit date:
2014-02-03

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