Thesis
Determining the structures of halogenated marine natural products by total synthesis
- Abstract:
-
Elatenyne, a brominated C15 acetogenin isolated from the red Laurencia elata marine algae, was originally assigned a pyranopyran structure. Previous total synthesis of the pyranopyran structure has found this assignment to be incorrect. During this work the revised 2,2’-bifuranyl skeleton of elatenyne was suggested, but this skeleton has 32 possible diastereomers. The most likely diastereomer of elatenyne was predicted using computational 13C NMR chemical shi...
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Funding
+ Engineering and Physical Sciences Research Council
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Funding agency for:
Dyson, B
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:31737a99-a13c-4110-b36d-1c043b66565b
- Local pid:
- ora:8482
- Deposit date:
- 2014-05-28
Terms of use
- Copyright holder:
- Bryony S Dyson
- Copyright date:
- 2011
- Notes:
- This thesis is not currently available via ORA. A major proportion of chapter 3 of this thesis is published in the following journal article: B. S. Dyson, J. W. Burton, T. I. Sohn, B. Kim, H. Bae, D. Kim, J. Am. Chem. Soc. 2012, 134, 11781-11790. [Available at http://dx.doi.org/10.1021/ja304554e]
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