Thesis icon

Thesis

Monocyte profile and function in sarcoidosis

Abstract:

Sarcoidosis is a multisystem inflammatory disorder of unknown aetiology. The immune pathology is characterised by dysregulated T cell (TH1) activity, macrophage activation and granuloma formation, resulting in systemic inflammation, and organ dysfunction. I hypothesised that, as the systemic precursor to the macrophage, altered monocyte activity in sarcoidosis may contribute to the early immune pathology of the disease. In this thesis, I examined their phenotype, four key monocy...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Ho group, Weatherall Institute of Molecular Medicine
Oxford college:
Jesus College
Role:
Author
More by this author
Division:
MSD
Department:
NDM
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
More from this funder
Funding agency for:
Crawshaw, A
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
UUID:
uuid:3378bf46-a494-45a0-b68e-81b37c1dae49
Local pid:
ora:9614
Deposit date:
2014-12-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP