New loci associated with kidney function and chronic kidney disease.

Journal article

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a meta-analysis of genome-wide association data in 67,093 individuals of European ancestry from 20 predominantly population-based studies in order to identify new susceptibility loci for reduced renal function as estimated by serum creatinine (eGFRcrea), serum cystatin c (eGFRcys) and CKD (eGFRcrea < 60 ml/min/1....

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Authors: Köttgen, A; Pattaro, C; Böger, C; Fuchsberger, C; Olden, M

• Publication status: Published
• Journal: Nature genetics
• Volume: 42
• Issue: 5
• Pages: 376-384
• Publication date: 2010-05-01
• DOI: 10.1038/ng.568
• EISSN: 1546-1718
• ISSN: 1061-4036
• Language: English
• Keywords: Cohort Studies; Glomerular Filtration Rate; Kidney Failure, Chronic; Kidney; Cystatin C; Genetic Markers; Models, Genetic; Risk Factors; Creatinine; Diet; Humans; Europe; Genome-Wide Association Study