Asymmetric syntheses of β- and γ-amino acids

Thesis

This thesis is concerned with the development of new synthetic routes for the asymmetric syntheses of a range of β- and γ-amino acids.

Chapter 1 introduces the various biological activities displayed by cyclic β-amino acid containing compounds together with their occurrence in pharmaceutical molecules and β-peptides. Some of the most commonly used synthetic strategies for the preparation of carbocyclic β-amino acids are briefly described, with the focus on the formation and function...

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Authors: Zammit, C

• Publication date: 2015
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: organic chemistry; asymmetric synthesis; methodology; organic synthesis; amino acid synthesis; synthetic organic chemistry
• Subjects: Chemistry & allied sciences; Polymers Amino acid and peptide chemistry; Organic chemistry; Physical Sciences; Synthetic organic chemistry; Organic synthesis