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Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions

Abstract:

Neonatal sepsis is a major cause of infant mortality in developing countries because of delayed injectable treatment, making it urgent to develop noninjectable formulations that can reduce treatment delays in resource-limited settings. Ceftriaxone, available only for injection, needs absorption enhancers to achieve adequate bioavailability via nonparenteral administration. This article presents all available data on the nonparenteral absorption of ceftriaxone in humans and animals, including ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/AAC.01170-18

Authors


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Publisher:
American Society for Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
62
Issue:
12
Article number:
e01170-18
Publication date:
2018-10-22
Acceptance date:
2018-09-26
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Pmid:
30348664
Source identifiers:
996262
Language:
English
Keywords:
Pubs id:
pubs:996262
UUID:
uuid:3571f63a-8fbb-49ea-9769-9f1b3e17c3ae
Local pid:
pubs:996262
Deposit date:
2019-06-14

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