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Journal article

Residual HIV-specific CD4 and CD8 T cell frequencies after prolonged antiretroviral therapy reflect pretreatment plasma virus load.

Abstract:

BACKGROUND: Virus-specific cellular immune responses mediated by CD4 and CD8 T lymphocytes are thought to be central to the effective control of HIV-1 replication in vivo. However, quantitative correlations between HIV-specific T lymphocyte frequencies and plasma virus load (pVL) have proved difficult to establish in infected human individuals. This most likely reflects the complex interactions between the virus and these immune effector cells in the absence of treatment. OBJECTIVE: To asses...

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Publication status:
Published

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Journal:
AIDS (London, England)
Volume:
16
Issue:
17
Pages:
2317-2322
Publication date:
2002-11-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Source identifiers:
23986
Language:
English
Keywords:
Pubs id:
pubs:23986
UUID:
uuid:359e71f8-072b-4dc1-8fa0-bbd0fc1bd605
Local pid:
pubs:23986
Deposit date:
2012-12-19

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