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What evidence is used to underpin the design of strength-based exercise interventions evaluated in randomised controlled trials for rheumatoid arthritis? A systematic review protocol

Abstract:
Introduction Healthcare researchers designing strength-based exercise interventions must choose an appropriate dose to test before evaluating its effect using a definitive/phase-III randomised controlled trial (RCT). Compared with early phase testing employed by pharmaceutical trials, it is questionable whether exercise-based trials employ the same rigour for establishing tolerated dosage. Consequently, it is unclear if participants are initially prescribed optimal doses of e... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjopen-2018-024127

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0003-0638-0406
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author
ORCID:
0000-0002-7801-5777
Expand authors...
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Journal website
Volume:
8
Pages:
e024127
Publication date:
2018-09-10
Acceptance date:
2018-07-30
DOI:
EISSN:
2044-6055
Pmid:
30206094
Source identifiers:
919709
Language:
English
Keywords:
Pubs id:
pubs:919709
UUID:
uuid:35ba5467-7e57-428b-bf51-9183e8b99851
Local pid:
pubs:919709
Deposit date:
2018-10-11

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