Journal article
Macrophages: micromanagers of antagonistic signaling nanoclusters
- Abstract:
- How cells integrate antagonistic receptor signaling events is enigmatic. Using superresolution optical microscopy, Lopes et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608094) demonstrate the nanometer-scale molecular reorganization of antagonistic signaling receptors in macrophages, after engagement by the receptors of activating and inhibitory ligands. They propose that large-scale rearrangements of this type underpin decision-making by these cells.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 658.5KB)
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- Publisher copy:
- 10.1083/jcb.201702028
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Authors
Funding
Medical Research Council
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Wellcome Trust
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Bibliographic Details
- Publisher:
- Rockefeller University Press Publisher's website
- Journal:
- Journal of Cell Biology Journal website
- Volume:
- 216
- Issue:
- 4
- Pages:
- 871-873
- Publication date:
- 2017-03-22
- DOI:
- EISSN:
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1540-8140
- ISSN:
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0021-9525
- Source identifiers:
-
687020
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:687020
- UUID:
-
uuid:35c059ad-0763-4ddd-b7b1-a6d5009542c4
- Local pid:
- pubs:687020
- Deposit date:
- 2017-06-14
Terms of use
- Copyright holder:
- © 2017 Eggeling and Davis
- Copyright date:
- 2017
- Notes:
-
This article is distributed under the terms of an Attribution–
Noncommercial–Share Alike–No Mirror Sites license for the first six months after the
publication date (see http://www.rupress.org/terms/). After six months it is available under
a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
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