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Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials.

Abstract:

BACKGROUND: There is uncertainty about the efficacy of lamotrigine in bipolar depressive episodes. AIMS: To synthesise the evidence for the efficacy of lamotrigine in bipolar depressive episodes. METHOD: Systematic review and meta-analysis of individual patient data from randomised controlled trials comparing lamotrigine with placebo. RESULTS: Individual data from 1072 participants from five randomised controlled trials were obtained. More individuals treated with lamotrigine than placebo res...

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Publication status:
Published

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Publisher copy:
10.1192/bjp.bp.107.048504

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
British journal of psychiatry : the journal of mental science
Volume:
194
Issue:
1
Pages:
4-9
Publication date:
2009-01-01
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
Source identifiers:
98077
Language:
English
Keywords:
Pubs id:
pubs:98077
UUID:
uuid:35db7ed5-d566-43dc-9bd1-0de1fed1062e
Local pid:
pubs:98077
Deposit date:
2012-12-19

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