Journal article
Impact of heterogeneity and effect size on the estimation of the optimal information size: analysis of recently published meta-analyses
- Abstract:
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Objective: To estimate the proportion of systematic reviews that meet the optimal information size (OIS) and assess the impact heterogeneity and effect size have on the OIS estimate by type of outcome (eg, mortality, semiobjective or subjective).
Methods: We carried out searches of Medline and Cochrane to retrieve meta-analyses published in systematic reviews from 2010 to 2012. We estimated the OIS using Trial Sequential Analysis software (TSA V.0.9) and based on several h...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.3MB)
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- Publisher copy:
- 10.1136/bmjopen-2017-015888
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Authors
Funding
National Institute for Health Research
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Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- BMJ Open Journal website
- Volume:
- 7
- Issue:
- 11
- Pages:
- 1-9
- Publication date:
- 2017-11-01
- Acceptance date:
- 2017-07-14
- DOI:
- ISSN:
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2044-6055
- Source identifiers:
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729913
Item Description
- Pubs id:
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pubs:729913
- UUID:
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uuid:36078f40-f5e7-449e-b269-7006934aeeb0
- Local pid:
- pubs:729913
- Deposit date:
- 2017-09-21
Terms of use
- Copyright holder:
- © Garcia-Alamino, et al (or their employer(s) unless otherwise stated in the text of the article) 2017
- Copyright date:
- 2017
- Notes:
- This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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