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Journal article

Meta-analysis of sex-specific genome-wide association studies.

Abstract:

Despite the success of genome-wide association studies, much of the genetic contribution to complex human traits is still unexplained. One potential source of genetic variation that may contribute to this "missing heritability" is that which differs in magnitude and/or direction between males and females, which could result from sexual dimorphism in gene expression. Such sex-differentiated effects are common in model organisms, and are becoming increasingly evident in human complex traits thr...

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Publication status:
Published

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Publisher copy:
10.1002/gepi.20540

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Genetic epidemiology
Volume:
34
Issue:
8
Pages:
846-853
Publication date:
2010-12-01
DOI:
EISSN:
1098-2272
ISSN:
0741-0395
Source identifiers:
97287
Language:
English
Keywords:
Pubs id:
pubs:97287
UUID:
uuid:3670713b-50f6-447f-8011-9051f90a3504
Local pid:
pubs:97287
Deposit date:
2012-12-19

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