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High resolution nuclear magnetic resonance studies of kringle containing proteins

Abstract:

The kringle is a name given to a sequence of seventy nine residues linked by three disulphide bridges, multiple copies of which have been found in a number of proteins involved in haemostasis. Kringles from plasminogen and prothrombin have been studied using high resolution nuclear magnetic resonance (NMR) spectroscopy.

Preliminary experiments demonstrated the kringles to be globular proteins in aqueous solution having well defined tertiary folds. Resonances have been assigned in th...

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Institution:
University of Oxford
Division:
MPLS
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
1983
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Source identifiers:
603839559
Language:
English
Subjects:
UUID:
uuid:36904eb5-3e22-4a62-86b1-f7cf1fa0cce6
Local pid:
td:603839559
Deposit date:
2013-10-21

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