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Substrates and physiological functions of secretase rhomboids proteases

Abstract:

Rhomboids are conserved intramembrane serine proteases with widespread functions. They were the earliest discovered members of the wider rhomboid-like superfamily of proteases and pseudoproteases. The secretase class of rhomboid proteases, distributed through the secretory pathway, are the most numerous in eukaryotes, but our knowledge of them is limited. Here we aim to summarise all that has been published on secretase rhomboids in a concise encyclopaedia of the enzymes, their substrates, an...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.semcdb.2016.07.033

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Institution:
University of Oxford
Oxford college:
Lincoln College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Funding agency for:
Grieve, A
Grant:
659166
Publisher:
Elsevier Publisher's website
Journal:
Seminars in Cell and Developmental Biology Journal website
Volume:
60
Pages:
10-18
Publication date:
2016-08-01
Acceptance date:
2016-07-31
DOI:
EISSN:
1096-3634
ISSN:
1084-9521
Source identifiers:
637272
Pubs id:
pubs:637272
UUID:
uuid:36a60a7c-1a44-43eb-95e6-75c5384fb141
Local pid:
pubs:637272
Deposit date:
2016-08-03

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