Thesis
TbISWI and its role in transcriptional control in Trypanosoma brucei
- Abstract:
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ISWI is a member of a versatile family of ATP-dependent chromatin remodelling complexes involved not only in transcription regulation (initiation, elongation and termination), but also in other cellular functions like maintenance of higher order chromatin structure and DNA replication. TbISWI, a novel ATPase of the ISWI family in Trypanosoma brucei, is involved in the transcriptional repression of silent VSG expression sites (ESs) in both bloodstream form (BF) and procyclic form ...
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Bibliographic Details
- Publication date:
- 2010
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:36aedf26-7bbc-4f29-9fa5-fc57c9477c23
- Local pid:
- ora:6055
- Deposit date:
- 2012-02-08
Terms of use
- Copyright holder:
- Kushwaha, M
- Copyright date:
- 2010
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