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Journal article

Recent advances in dengue pathogenesis and clinical management.

Abstract:

This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.vaccine.2015.09.103

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
33
Issue:
50
Pages:
7061-7068
Publication date:
2015-10-14
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Source identifiers:
581207
Language:
English
Keywords:
Pubs id:
pubs:581207
UUID:
uuid:36afb3d4-01eb-4e3e-89bf-a3bb2b7fc76a
Local pid:
pubs:581207
Deposit date:
2016-02-16

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