Journal article
Correcting the standard errors of 2-stage residual inclusion estimators for Mendelian randomization studies
- Abstract:
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Mendelian randomization studies use genotypes as instrumental variables to test for and estimate the causal effects of modifiable risk factors on outcomes. Two-stage residual inclusion (TSRI) estimators have been used when researchers are willing to make parametric assumptions. However, researchers are currently reporting uncorrected or heteroscedasticity-robust standard errors for these estimates. We compared several different forms of the standard error for linear and logistic TSRI estimate...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 540.9KB)
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- Publisher copy:
- 10.1093/aje/kwx175
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Authors
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- American Journal of Epidemiology Journal website
- Volume:
- 186
- Issue:
- 9
- Pages:
- 1104-1114
- Publication date:
- 2017-06-01
- Acceptance date:
- 2016-12-21
- DOI:
- EISSN:
-
1476-6256
- ISSN:
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0002-9262
- Pmid:
-
29106476
- Source identifiers:
-
747471
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:747471
- UUID:
-
uuid:36b82526-e8bb-457a-b1f7-0cac2bd6c3c6
- Local pid:
- pubs:747471
- Deposit date:
- 2019-02-27
Terms of use
- Copyright holder:
- Palmer et al
- Copyright date:
- 2017
- Notes:
- © The Authors 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journalpermissions@oup.com.
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