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Journal article : Review

International union of basic and clinical pharmacology. CVIII. Calcium-sensing receptor nomenclature, pharmacology, and function

Abstract:

The calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor that responds to multiple endogenous agonists and allosteric modulators, including divalent and trivalent cations, L-amino acids, γ-glutamyl peptides, polyamines, polycationic peptides, and protons. The CaSR plays a critical role in extracellular calcium (Ca2+ o) homeostasis, as demonstrated by the many naturally occurring mutations in the CaSR or ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1124/pr.119.018531

Authors


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Institution:
University of Oxford
Division:
MSD
Sub department:
Women's & Reproductive Health
Role:
Author
ORCID:
0000-0002-2975-5170
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Department of Health More from this funder
Publisher:
American Society for Pharmacology and Experimental Therapeutics (ASPET) Publisher's website
Journal:
Pharmacological Reviews Journal website
Volume:
72
Issue:
3
Pages:
558-604
Publication date:
2020-05-28
Acceptance date:
2020-02-27
DOI:
EISSN:
1521-0081
ISSN:
0031-6997
Pmid:
32467152
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1109024
Local pid:
pubs:1109024
Deposit date:
2021-03-18

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