Journal article icon

Journal article

Selection of appropriate metagenome taxonomic classifiers for ancient microbiome research

Abstract:

Metagenomics enables the study of complex microbial communities from myriad sources, including the remains of oral and gut microbiota preserved in archaeological dental calculus and paleofeces, respectively. While accurate taxonomic assignment is essential to this process, DNA damage characteristic of ancient samples (e.g., reduction in fragment size and cytosine deamination) may reduce the accuracy of read taxonomic assignment. Using a set of in silico-generated metagenomic data sets, we inv...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1128/mSystems.00080-18

Authors


More by this author
Institution:
University of Oxford
Division:
Social Sciences Division
Department:
School of Archaeology; Archaeology Institute
Department:
Oxford,SSD,SchoolofArchaeology,ArchaeologyInstitute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Social Sciences Division
Department:
School of Archaeology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Social Sciences Division
Department:
School of Archaeology
Role:
Author
More from this funder
Funding agency for:
Larson, G
Grant:
ERC-2013-StG-337574-UNDEAD
John Fell Fund More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
mSystems Journal website
Volume:
3
Issue:
4
Publication date:
2018-07-17
Acceptance date:
2018-06-20
DOI:
ISSN:
2379-5077
Source identifiers:
889554
Keywords:
Pubs id:
pubs:889554
UUID:
uuid:36d7e985-e6f0-4006-a6fe-c1c5060bfc85
Local pid:
pubs:889554
Deposit date:
2018-07-20

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP