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Journal article

Plasma cytokines and risk of coronary heart disease in the PROCARDIS study

Abstract:
Objective The aims of the study were to examine the associations of plasma levels of five cytokines (interleukin (IL)-6, IL-5, interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α) and IL-6 receptor (IL-6R)) and C reactive protein (CRP) with risk of coronary heart disease (CHD). Methods: In a case–control study of 931 CHD cases and 974 controls, logistic regression was used to estimate the OR and 95% CI of CHD for extreme thirds of biomarkers after ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/openhrt-2018-000807

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
Role:
Author
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Funding agency for:
Hopewell, J
Grant:
FS/14/55/30806
More from this funder
Grant:
LSHM-CT-2007–037273
AstraZeneca More from this funder
British Heart Foundation Oxford Centre of Research Excellence More from this funder
British Heart Foundation More from this funder
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Publisher:
BMJ Publishing Group Publisher's website
Journal:
Open Heart Journal website
Volume:
5
Issue:
1
Article number:
e000807
Publication date:
2018-04-25
Acceptance date:
2018-04-04
DOI:
ISSN:
2053-3624
Source identifiers:
835111
Keywords:
Pubs id:
pubs:835111
UUID:
uuid:36dbce59-b78e-43c8-92a2-992a502c6a29
Local pid:
pubs:835111
Deposit date:
2018-04-11

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