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Journal article

Analyses of cancer data from three ezetimibe trials.

Abstract:

BACKGROUND: Five years of statin therapy lowers low-density lipoprotein (LDL) cholesterol substantially and, over a 5-year period, results in reductions in the incidence of cardiovascular events. The Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) trial (ClinicalTrials.gov number, NCT00092677) has raised the hypothesis that adding ezetimibe to statin therapy for larger LDL cholesterol reductions might increase the incidence of cancer. METHODS: We compared the results of a hypothesis-gener...

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Publication status:
Published

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Publisher copy:
10.1056/nejmsa0806603

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Journal:
New England journal of medicine
Volume:
359
Issue:
13
Pages:
1357-1366
Publication date:
2008-09-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Source identifiers:
34368
Language:
English
Keywords:
Pubs id:
pubs:34368
UUID:
uuid:370198d9-66b3-426a-8f92-42eedf6d5bae
Local pid:
pubs:34368
Deposit date:
2012-12-19

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