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Thesis

Differential macrophage polarization promotes entheseal bone formation in AS

Abstract:

Systemic and focal bone loss is a common feature of many forms of arthritis. However, inappropriate new bone formation also occurs in inflammatory arthritis, including ankylosing spondylitis (AS), osteoarthritis, and rheumatoid arthritis. These features are important signs of systemic inflammation in AS.

In general, inflammation is thought to inhibit bone-forming osteoblasts whilst promoting the formation and activation of osteoclasts. More recently, macrophages have been recognized...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:3720988d-0b56-4089-a680-cc15e9c91984
Deposit date:
2018-10-15

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