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Journal article

Defensive function of transposable elements in bacteria

Abstract:

It has been widely debated whether transposable elements have a positive or a negative effect on their host cells. This study demonstrated that transposable elements, specifically insertion sequences (ISs), can adopt a defensive role in Escherichia coli. IS1 and IS10 in three different E. coli strains (S17, DH5a and Nissle 1917) rapidly disrupted the I-CeuI gene (encoding I-CeuI endonuclease) on the plasmid pLO11-ICeuI as early as the 1st generation, despite th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/acssynbio.9b00218

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Publisher:
American Chemical Society Publisher's website
Journal:
ACS Synthetic Biology Journal website
Volume:
8
Issue:
9
Pages:
2141-2151
Publication date:
2019-08-02
Acceptance date:
2019-08-02
DOI:
EISSN:
2161-5063
Source identifiers:
1038439
Language:
English
Keywords:
Pubs id:
pubs:1038439
UUID:
uuid:372f1259-be24-4898-a3b1-e9457cfec19e
Local pid:
pubs:1038439
Deposit date:
2019-08-05

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