Finite element simulation of a poroelastic model of the CSF system in the human brain during an infusion test

Thesis

Cerebrospinal fluid (CSF) fills a system of cavities at the centre of the brain, known as ventricles, and the subarachnoid space surrounding the brain and the spinal cord. In addition, CSF is in free communication with the interstitial fluid of the brain tissue. Disturbances in CSF dynamics can lead to diseases that cause severe brain damage or even death. So-called infusion tests are frequently performed in the diagnosis of such diseases. In this type of test, changes in average CSF press...

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Authors: Eisenträger, A; Almut Eisentraeger

• Publication date: 2012
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: Oxford University, UK
• Language: English
• Keywords: poroelasticity; cerebrospinal fluid; brain; hydrocephalus; infusion test
• Subjects: Fluid mechanics (mathematics); Mechanics of deformable solids (mathematics); Biology and other natural sciences (mathematics); Mathematical biology; Computer science (mathematics)