Thesis
Structural studies of PfEMP1 bound to human cluster of differentiation 36 and of an unusual human antibody
- Abstract:
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In Plasmodium falciparum-infected humans, parasites escape from splenic clearance and cause severe or chronic symptoms partly through the action of the variable surface antigens expressed on the surfaces of infected erythrocytes, called P. falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 that interact with human Cluster of Differentiation 36 (CD36) receptor mediate the most common adhesion phenotype found in infected erythrocytes. Here the firs...
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Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
-
uuid:373f04b8-6ca9-4c51-8170-4bb4e6238920
- Deposit date:
- 2017-11-29
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Terms of use
- Copyright holder:
- Hsieh, F
- Copyright date:
- 2017
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