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Protection, pathogenesis and phenotypic plasticity in Plasmodium falciparum malaria.

Abstract:

Why does Plasmodium falciparum cause severe illness in some but not all infections? How is clinical immunity acquired? These questions have intrigued investigators since the clinical epidemiology of malaria was first described. The search for answers to both questions has highlighted the changes that take place at the surface of infected red blood cells during the last half of the erythrocytic cycle. These changes specify the antigenic and adhesive or cytoadherence phenotypes for the infected...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
Journal:
Parasitology today (Personal ed.)
Volume:
9
Issue:
8
Pages:
281-286
Publication date:
1993-08-01
DOI:
ISSN:
0169-4758
Source identifiers:
30495
Language:
English
Pubs id:
pubs:30495
UUID:
uuid:375c23e0-c597-496c-abb4-e5fa7f042123
Local pid:
pubs:30495
Deposit date:
2012-12-19

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