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Journal article

Variation across the allele frequency spectrum.

Abstract:
A new study finds that individuals with high plasma triglyceride levels carry approximately twice as many rare, coding genetic variants within four candidate genes identified through genome-wide association studies than individuals without these high levels. This study demonstrates the overlap of rare and common variant signals at loci associated with lipid levels and shows the value of efforts to extend susceptibility variant discovery to embrace the full allele-frequency spectrum. © 2010 Nature America, Inc. All rights reserved.
Publication status:
Published

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Publisher copy:
10.1038/ng0810-648

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Nature genetics
Volume:
42
Issue:
8
Pages:
648-650
Publication date:
2010-08-01
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Source identifiers:
65923
Language:
English
Keywords:
Pubs id:
pubs:65923
UUID:
uuid:377e4a28-d228-4a77-b299-38e2605354ba
Local pid:
pubs:65923
Deposit date:
2012-12-19

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