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Classification of fumarate reductases and succinate dehydrogenases based upon their contrasting behaviour in the reduced benzylviologen/fumarate assay.

Abstract:

Reduction of fumarate by soluble beef heart succinate dehydrogenase has been shown previously by voltammetry to become increasingly retarded as the potential is lowered below a threshold potential of -80 mV at pH 7.5. The behaviour resembles that of a tunnel diode, an electronic device exhibiting the property of negative resistance. The enzyme thus acts to oppose fumarate reduction under conditions of high thermodynamic driving force. We now provide independent evidence for this phenomenon fr...

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Publication status:
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
Journal:
FEBS letters
Volume:
326
Issue:
1-3
Pages:
92-94
Publication date:
1993-07-01
DOI:
EISSN:
1873-3468
ISSN:
0014-5793
Source identifiers:
46009
Language:
English
Keywords:
Pubs id:
pubs:46009
UUID:
uuid:378d5cb0-e84f-405d-987d-c896fca61184
Local pid:
pubs:46009
Deposit date:
2013-11-17

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