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Nitrite protects mitochondrial structure and function under hypoxia

Abstract:

Oxygen deprivation leads to changes in mitochondrial morphology and impaired flow of reducing equivalents through the electron transport chain. The extent of these changes depends on the duration and severity of the treatment as well as on the species and cell type. Nitrate is known to ameliorate these effects in some instances but it is possible that it is nitrite, rather than nitrate, that is the key to the mechanism. To test this, mitochondria were isolated from 21 d old pea (Pisum sativu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/pcp/pcw174

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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
Publisher:
Oxford University Press Publisher's website
Journal:
Plant and Cell Physiology Journal website
Volume:
58
Issue:
1
Pages:
175–183
Publication date:
2016-10-01
Acceptance date:
2016-10-11
DOI:
EISSN:
1471-9053
ISSN:
0032-0781
Keywords:
Pubs id:
pubs:653060
UUID:
uuid:3798259e-3236-4883-bdd8-2e1689e8e97c
Local pid:
pubs:653060
Source identifiers:
653060
Deposit date:
2016-10-20

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