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Journal article

Cytokine profiles during invasive nontyphoidal Salmonella disease predict outcome in African children.

Abstract:: Nontyphoidal Salmonella is a leading cause of sepsis in African children. Cytokine responses are central to the pathophysiology of sepsis and predict sepsis outcome in other settings. In this study, we investigated cytokine responses to invasive nontyphoidal Salmonella (iNTS) disease in Malawian children. We determined serum concentrations of 48 cytokines with multiplexed immunoassays in Malawian children during acute iNTS disease (n = 111) and in convalescence (n = 77). Principal component a...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Gilchrist, J., Heath, J., Msefula, C., Gondwe, E., Naranbhai, V., Mandala, W., MacLennan, J., Molyneux, E., Graham, S., Drayson, M., Molyneux, M., & MacLennan, C. (2016). Cytokine profiles during invasive nontyphoidal Salmonella disease predict outcome in African children. Clinical and Vaccine Immunology, 23(7), 601–609.

MLA Style

Gilchrist, J., et al. “Cytokine Profiles during Invasive Nontyphoidal Salmonella Disease Predict Outcome in African Children.” Clinical and Vaccine Immunology, edited by D Pascual, vol. 23, no. 7, American Society for Microbiology, 2016, pp. 601–09.

Chicago Style

Gilchrist, J, J Heath, C Msefula, E Gondwe, V Naranbhai, W Mandala, J MacLennan, et al. 2016. “Cytokine Profiles during Invasive Nontyphoidal Salmonella Disease Predict Outcome in African Children.” Edited by D Pascual. Clinical and Vaccine Immunology 23 (7): 601–9.
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Files:: Cytokine Profiles duri...

(Version of record, pdf, 2.1MB)

Publisher copy:: 10.1128/cvi.00128-16

Authors

+ Gilchrist, J More by this author

Institution:

University of Oxford

Division:

Medical Sciences Division

Department:

Paediatrics

Role:

Author

+ Heath, J More by this author

Role:

Author

+ Msefula, C More by this author

Role:

Author

+ Gondwe, E More by this author

Role:

Author

+ Naranbhai, V More by this author

Role:

Author

More authors...

Contributors

Role:

Editor

Funding

+ Wellcome Trust More from this funder

Grant:

074124/Z/04/Z

Bill and Melinda Gates Foundation More from this funder

GlaxoSmithKline More from this funder

Bibliographic Details

Publisher:: American Society for Microbiology Publisher's website
Journal:: Clinical and Vaccine Immunology Journal website
Volume:: 23
Issue:: 7
Pages:: 601-609
Publication date:: 2016-05-01
Acceptance date:: 2016-05-07
DOI:: 10.1128/cvi.00128-16
EISSN:: 1556-679X
ISSN:: 1556-6811
Pmid:: 27170644

Item Description

Language:: English
Keywords:: Macrophages

Adolescent

Male

Infant, Newborn

Humans

Malnutrition

Salmonella Infections

Survival Analysis

Neutrophils

Child

Cytokines

Malawi

Child, Preschool

HIV Infections

Sepsis

Infant

Female
Pubs id:: pubs:623178
UUID:: uuid:37a34d07-c4a0-4fd0-9ab5-a22da0cc9733
Local pid:: pubs:623178
Source identifiers:: 623178
Deposit date:: 2017-10-17

Terms of use

Copyright holder:: Gilchrist et al
Copyright date:: 2016
Notes:: Copyright © 2016 Gilchrist et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Licence:: CC Attribution (CC BY)

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