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Journal article

Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis

Abstract:

Red cells play a key role in normal haemostasis in vitro but their importance clinically is less clear. The objective of this meta-analysis was to assess if correction of anaemia by transfusing red cells at a high haemoglobin threshold (liberal transfusion) is superior to transfusion at a lower haemoglobin threshold (restrictive transfusion) for reducing the risk of bleeding or thrombotic events. We searched for randomized controlled trials in any clinical setting that compared two red cell t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1160/TH17-01-0015

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Funding agency for:
Trivella, M
Grant:
CochraneProgrammeGrant-Safe
AppropriateUseofBloodComponents
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Funding agency for:
Hopewell, S
Grant:
CochraneProgrammeGrant-Safe
AppropriateUseofBloodComponents
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Funding agency for:
Estcourt, L
Grant:
AppropriateUseofBloodComponents
CochraneProgrammeGrant-Safe
Publisher:
Schattauer Publisher's website
Journal:
Thrombosis and Haemostasis Journal website
Volume:
2017
Issue:
5
Pages:
889-898
Publication date:
2017-03-02
Acceptance date:
2017-02-02
DOI:
ISSN:
0340-6245
Source identifiers:
677383
Keywords:
Pubs id:
pubs:677383
UUID:
uuid:37b01602-cd5d-485a-837f-fb3c52ca91c2
Local pid:
pubs:677383
Deposit date:
2017-02-08

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