Journal article icon

Journal article

Effects on hepatic lipid metabolism in human hepatoma cells following overexpression of TGFβ induced factor homeobox 1 or 2

Abstract:

Transforming growth factor β induced factor homeobox (TGIF) 1 and 2 are two transcriptional repressors. Although TGIF1 has been found to be involved in lipid metabolism, no studies have yet investigated the role of TGIF2 in hepatic lipid metabolism. Here we aim to investigate effects on hepatic lipid metabolism following overexpression of the human and mouse TGIF1 and TGIF2 protein. We used modified mRNA molecules to transiently enhance the expression of these proteins in human hepatoma cells...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1016/j.bbalip.2019.02.009

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
ORCID:
0000-0002-2648-6526
Publisher:
Elsevier Publisher's website
Journal:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Journal website
Volume:
1864
Issue:
5
Pages:
756-762
Publication date:
2019-02-27
Acceptance date:
2019-02-25
DOI:
ISSN:
1879-2618
Pmid:
30825648
Source identifiers:
981011
Language:
English
Keywords:
Pubs id:
pubs:981011
UUID:
uuid:37cc187a-deb6-48b9-ace6-383d58230d7e
Local pid:
pubs:981011
Deposit date:
2019-03-20

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP