Inflammation and frailty in the elderly: A systematic review and meta-analysis.
The pathogenesis of frailty and the role of inflammation is poorly understood. We examined the evidence considering the relationship between inflammation and frailty through a systematic review and meta-analysis. A systematic literature search of papers providing data on inflammatory biomarkers and frailty was carried out in major electronic databases from inception until May 2016. From 1856 initial hits, 35 studies (32 cross-sectional studies n=3232 frail, n=11,483 pre-frail and n=8522 robus...Expand abstract
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- Peer review status:
- Peer reviewed
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- Soysal et al
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- © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license.
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