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Interphase nuclei of many mammalian cell types contain deep, dynamic, tubular membrane-bound invaginations of the nuclear envelope.

Abstract:

The nuclear envelope consists of a double-membraned extension of the rough endoplasmic reticulum. In this report we describe long, dynamic tubular channels, derived from the nuclear envelope, that extend deep into the nucleoplasm. These channels show cell-type specific morphologies ranging from single short stubs to multiple, complex, branched structures. Some channels transect the nucleus entirely, opening at two separate points on the nuclear surface, while others terminate at or close to n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1083/jcb.136.3.531

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More from this funder
Funding agency for:
Vaux, D
Publisher:
Rockefeller University Press Publisher's website
Journal:
Journal of Cell Biology Journal website
Volume:
136
Issue:
3
Pages:
531-544
Publication date:
1997-02-01
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
Source identifiers:
53072
Language:
English
Keywords:
Pubs id:
pubs:53072
UUID:
uuid:38165aa9-8a4d-40ec-aff6-0e128ecd6ae9
Local pid:
pubs:53072
Deposit date:
2012-12-19

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