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The dynamics of centrosome assembly in the early Drosophila embryo

Abstract:

Centrosomes are important for many cellular processes. They comprise of a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). In Drosophila, although more than hundreds of proteins localise to PCM, it is believed that the PCM assembly is governed by a small subset of proteins—Polo, Spd-2 and Cnn forming a network-like underlying scaffold. This scaffold appears to be plastic and adopts different behaviours in many cell types. Therefore, Drosophila centrosomes allow ...

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Division:
MSD
Role:
Author

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Supervisor
Balliol College, University of Oxford More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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Deposit date:
2021-08-04

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