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Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.

Abstract:

Resting CD45RO+, mature/memory, T cells are phenotypically distinct from intermediate CD45RO+/CD45RA+ and CD45RA+, immature/virgin, T cells, and are characterized by high levels of expression of a number of adhesion molecules, such as CD2, CD18, CD58 and CD29. The kinetics of up-regulation of molecules, like CD25 and CD54 associated with activation, were similar in both subsets and suggested that their high level expression was associated with later events rather than initial recognition and ...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Immunology
Volume:
69
Issue:
3
Pages:
460-467
Publication date:
1990-03-01
EISSN:
1365-2567
ISSN:
0019-2805
Source identifiers:
34841

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