Journal article
Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara.
- Abstract:
-
Malaria is a major global health problem for which an effective vaccine is required urgently. Prime-boost vaccination regimes involving plasmid DNA and recombinant modified vaccinia virus Ankara-encoding liver-stage malaria antigens have been shown to be powerfully immunogenic for T cells and capable of inducing partial protection against experimental malaria challenge in humans, manifested as a delay in time to patent parasitemia. Here, we report that substitution of plasmid DNA as the primi...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.0406381102
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 102
- Issue:
- 13
- Pages:
- 4836-4841
- Publication date:
- 2005-03-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
33033
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:33033
- UUID:
-
uuid:3855a112-9cbf-4b5e-b35a-94e94afaf308
- Local pid:
- pubs:33033
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2005
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