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Journal article

Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(+) T-cell responses which can be defined to the epitope level.

Abstract:
We measured CD8(+) T-cell responses in 12 potentially exposed but uninfected men who have sex with men by using cytokine flow cytometry. Four of the individuals screened exhibited polyfunctional immune responses to human immunodeficiency virus type 1 Gag or Vif. The minimum cytotoxic T lymphocyte epitope was mapped in one Gag responder.
Publication status:
Published

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Publisher copy:
10.1128/cvi.00247-08

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Journal:
Clinical and vaccine immunology : CVI
Volume:
15
Issue:
11
Pages:
1745-1748
Publication date:
2008-11-01
DOI:
EISSN:
1556-679X
ISSN:
1556-6811
Source identifiers:
131172
Language:
English
Keywords:
Pubs id:
pubs:131172
UUID:
uuid:385ee960-33d2-4757-a82d-b0d5ac4fbdc2
Local pid:
pubs:131172
Deposit date:
2012-12-19

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