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Journal article

Celebrating Soft Matter's 10th Anniversary: Cell division: a source of active stress in cellular monolayers.

Abstract:

We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies. Extending the hydrodynamic models of lyotropic active nematics we describe turbulent-like velocity fields that are generated by the cell division in a confluent monolayer of cells. We show that the experimentally measured flow field of dividing Madin-Darby Canine Kidney (MDCK) cells is reproduced by our modeling approach. Divisi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c5sm01382h

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Theoretical Physics
Role:
Author
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Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Soft matter Journal website
Volume:
11
Issue:
37
Pages:
7328-7336
Publication date:
2015-10-01
DOI:
EISSN:
1744-6848
ISSN:
1744-683X
Source identifiers:
539665
Language:
English
Pubs id:
pubs:539665
UUID:
uuid:38807541-9d64-43d1-837a-5430140526a0
Local pid:
pubs:539665
Deposit date:
2015-12-21

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